New ELISA tests for EPM diagnosis developed at the Gluck Center are exclusive to EDS

Diagnostic assays for equine protozoal myeloecephalitis (EPM) developed under the leadership of Daniel Howe, PhD, a molecular parasitologist at the University of Kentucky Gluck Equine Research Center, are now available exclusively at Equine Diagnostic Solutions, LLC (EDS).

The new diagnostic tests are quantitative enzyme-linked immunosorbent assays (ELISAs) based on multiple immunogenic proteins located on the surface of the Sarcocystis neurona parasite. Horses that get infected with S. neurona produce a vigorous antibody response to these parasite proteins, which can be accurately measured with the ELISAs.

“Recent studies have demonstrated the clinical utility of the new tests for the accurate diagnosis of EPM,” Howe said. “Specifically, by using the ELISAs to compare the amount of antibody present in the serum versus the cerebrospinal fluid of a horse, it is now possible to achieve a much more reliable assessment of whether the horse is suffering from EPM.”

Howe joined the faculty at the Gluck Center in 1999 and heads a research program focused on the molecular biology of S. neurona, which causes the serious neurologic disease EPM.

The research leading to the development of these assays was made possible by funds to Howe’s laboratory from the Amerman Family Equine Research Endowment.

The development and validation of the diagnostic assays was a collaborative effort between Howe and Michelle Yeargan, research specialist, at the Gluck Center; Martin Furr, DVM, PhD, Dipl. ACVIM, Adelaide C. Riggs Chair in Equine Medicine at Virginia Tech; Steve Reed, DVM, a world-renowned expert in equine neurologic diseases at Rood & Riddle Equine Hospital; and Jennifer Morrow, PhD, and Amy Graves, MT(ASCP), at EDS.

University of Kentucky and Gluck Equine Research Foundation press release July2010

 

 

SAG2/3/4 ELISAs educational bulletin click here

 

 

Last Updated on Thursday, 16 September 2010 15:19
 
New ELISA tests for EPM diagnosis developed at the Gluck Center are exclusive to EDS

Diagnostic assays for equine protozoal myeloecephalitis (EPM) developed under the leadership of Daniel Howe, PhD, a molecular parasitologist at the University of Kentucky Gluck Equine Research Center, are now available exclusively at Equine Diagnostic Solutions, LLC (EDS).

The new diagnostic tests are quantitative enzyme-linked immunosorbent assays (ELISAs) based on multiple immunogenic proteins located on the surface of the Sarcocystis neurona parasite. Horses that get infected with S. neurona produce a vigorous antibody response to these parasite proteins, which can be accurately measured with the ELISAs.

“Recent studies have demonstrated the clinical utility of the new tests for the accurate diagnosis of EPM,” Howe said. “Specifically, by using the ELISAs to compare the amount of antibody present in the serum versus the cerebrospinal fluid of a horse, it is now possible to achieve a much more reliable assessment of whether the horse is suffering from EPM.”

Howe joined the faculty at the Gluck Center in 1999 and heads a research program focused on the molecular biology of S. neurona, which causes the serious neurologic disease EPM.

The research leading to the development of these assays was made possible by funds to Howe’s laboratory from the Amerman Family Equine Research Endowment.

The development and validation of the diagnostic assays was a collaborative effort between Howe and Michelle Yeargan, research specialist, at the Gluck Center; Martin Furr, DVM, PhD, Dipl. ACVIM, Adelaide C. Riggs Chair in Equine Medicine at Virginia Tech; Steve Reed, DVM, a world-renowned expert in equine neurologic diseases at Rood & Riddle Equine Hospital; and Jennifer Morrow, PhD, and Amy Graves, MT(ASCP), at EDS.

University of Kentucky and Gluck Equine Research Foundation press release July2010

 

 

SAG2/3/4 ELISAs educational bulletin click here

 

 

Last Updated on Thursday, 16 September 2010 15:19