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Articles, Abstracts & Publications

Publications:

C Gamage, A Graves, L Ganwu, CJ Thieulent, UBR Balasuriya, J Morrow, A Vissani, V Parreno, J Matthijnssens and M Carossino (2025) Coding-complete genome sequences of group B equine rotavirus from central Kentucky, USA, reveal circulation of a single genome constellation. Microbiol. Resour. Announc. Dec 11; 14(12):e0074425

CJ Angwin, I de Assis Rocha, SM Reed, JK Morrow, A Graves and DK Howe (2025) Analysis of IgG responses to Sarcocystis neurona in horses with equine protozoal myeloencephalitis (EPM) suggests a Th1-biased immune response. Veterinary Immunology and Immunopathology 289 (2025): 111009

F Payette, JC Kulp, A Graves, J Janes, J Morrow, K Orr, S Reed, R Ruby, D Stefanovski and AL Johnson (2025) Commercial cytokine assay on equine cerebrospinal fluid does not distinguish equine degenerative myeloencephalopathy from cervical vertebral stenotic myelopathy. Amer J of Veterinary Research Sep 5; 86(12):ajvr.25.06.0212

T Uprety, S Soni, C Sreenivasan, BM Hause, A Naveed, S Ni, AJ Graves, JK Morrow, N Meade, KH Mellits, E Adam, MA Kennedy, D Wang and F Li (2024) Genetic and antigenic characterization of two diarrhoeic dominant rotavirus A genotypes G3P[12] and G14P[12] circulating in the global equine population. J. General Virology 105:002016

CK Rodriquez, JK Morrow, A Graves and A Johnson (2023) Evaluation of real-time polymerase chain reaction for the diagnosis of protozoal myeloencephalitis in horses using cerebrospinal fluid. J. Veterinary Internal Medicine 37:1893-1898

KM Delph, LA Beard, AC Trimble, ME Sutter, JF Timoney and JK Morrow (2019) Strangles, convalescent Streptococcus equi subspecies equi M antibody titers, and presence of complications. J. Veterinary Internal Medicine 33:275-279

S Schale, D Howe, M Yeargan, JK Morrow, A Graves and AL Johnson (2018) Protozoal coinfection in horses with equine protozoal myeloencephalitis in the eastern United States. J. Veterinary Internal Medicine 32: 1210-1214

AR Intan-Shameha, TJ Divers, JK Morrow, A Graves, E Olsen, AL Johnson and HO Mohammed (2017) Phosphorylated neurofilament H (pNF-H) as a potential diagnostic marker for neurological disorders in horses. Research in Veterinary Science 114: 401-405

WJA Saville, JP Dubey, AE Marsh, SM Rees, RO Keene, DK Howe, J Morrow and JD Workman (2017) Testing the Sarcocystis neurona vaccine using an equine protozoal myeloencephalitis challenge model. Veterinary Parasitology 247: 37-41

SM Reed, M Furr, DK Howe, AL Johnson, RJ MacKay, JK Morrow, N Pusterla and S Witonsky (2016) Equine protozoal myeloencephalitis (EPM): an updated consensus statement with a focus on parasite biology, diagnosis, treatment and prevention. J. Veterinary Internal Medicine 30: 491-502

AC Renier, JK Morrow, AJ Graves, CJ Finno, DK Howe, SD Owens, E Tamez-Trevino, AE Packham, PA Conrad and N Pusterla (2016) Diagnosis of equine protozoal myeloencephalitis using indirect fluorescent antibody testing and enzyme-linked immunosorbent assay titer ratios for Sarcocystis neurona and Neospora hughesi. J. Equine Veterinary Science 36: 49-51

M Yeargan, I de Assis Rocha, J Morrow, A Graves, SM Reed and DK Howe (2015) A new trivalent SnSAG surface antigen chimera for efficient detection of antibodies against Sarcocystis neurona and diagnosis of equine protozoal myeloencephalitis. J. Veterinary Diagnostic Investigation 27:377-381

SM Reed, DK Howe, JK Morrow, A Graves, MR Yeargan, AL Johnson, RJ MacKay, M Furr, WJA Saville and NM Williams (2013) Accurate Antemortem Diagnosis of Equine Protozoal Myeloencephalitis (EPM) Based on Detecting Intrathecal Antibodies against Sarcocystis neurona Using the SnSAG2 and SnSAG4/3 ELISAs. J. Veterinary Internal Medicine 27:1193-1200

AL Johnson, JK Morrow and RW Sweeney (2013). Indirect fluorescent antibody test and surface antigen ELISAs for antemortem diagnosis of equine protozoal myeloencephalitis. J. Vet. Intern. Med. 27:596-599

CM Brown, JK Morrow, CL Carleton, B Ramanathan, R Reddy, V Vaidya, SM Karthikeyan, AA Zulfikar and VS Kannadkar (2006) Persistence of serum antibodies to Sarcocystis neurona in horses moved from North America to India. J. Veterinary Internal Medicine 20: 994-997

JS Hoane, JK Morrow, WJ Saville, JP Dubey, DE Granstrom and DK Howe (2005) Enzyme-linked immunosorbent assays for the detection of equine antibodies specific to Sarcocystis neurona surface antigens. Clinical and Diagnostic Laboratory Immunology 12: 1050-1056

JS Hoane, MR Yeargen, S Stamper, WS Saville, JK Morrow, DS Lindsay and DK Howe (2005) Recombinant NhSAG1 ELISA: a sensitive and specific assay for detecting antibodies against Neospora hughesi in equine serum. J. Parasitology 91: 446-452

S Witonsky, JK Morrow, C Leger, J Dascanio, V Buechner-Maxwell, W Palmer, K Kline and A Cook (2004) Sarcocystis neurona- specific immunoglobulin G in the serum and cerebrospinal fluid of horses administered the S. neurona vaccine. J. Veterinary Internal Medicine 18: 98-103

JP Dubey, SM Mitchell, JK Morrow, JC Rhyan, LM Stewart, DE Granstrom, S Romand, P Thulliez, WJ Saville and DS Lindsay (2003) Prevalence of antibodies to Neospora caninum, Sarcocystis neurona and Toxoplasma gondii in wild horses from central Wyoming. J. Parasitology 89: 716-720

BG Bentz, KA Ealey, J Morrow, PL Claypool and JT Saliki (2003) Seroprevalence of antibodies to Sarcocystis neurona in equids residing in Oklahoma. J. Veterinary Diagnostic Investigation 15: 597-600

BM Daft, BC Barr, IA Gardner, D Read, W Bell, KG Peyser, A Ardans, H Kinde and JK Morrow (2002) Sensitivity and specificity of western blot testing of cerebrospinal fluid and serum for diagnosis of equine protozoal myeloencephalitis in horses with and without neurologic abnormalities. JAVMA 221: 1007-1013

AG Cook, V Buechner-Maxwell, LL Donaldson, NA Parker, DL Ward and JK Morrow (2002) Detection of antibodies against Sarcocystis neurona in cerebrospinal fluid from clinically normal neonatal foals. JAVMA 220: 208-211

AG Cook, V Buechner-Maxwell, JK Morrow, DL Ward, NA Parker, JJ Dascanio, WB Ley and W Cooper (2001) Interpretation of the detection of Sarcocystis neurona antibodies in the serum of young horses. Veterinary Parasitology 95: 187-195

MM Miller, CR Sweeney, GE Russell, RM Sheetz and JK Morrow (1999) Effects of blood contamination of cerebrospinal fluid on western blot analysis for Sarcocystis neurona and on albumin quotient and immunoglobulin G index in horses. Journal American Veterinary Medical Association [JAVMA] 215: 67–70

Abstracts and Oral Presentations

J Soto, I de Assis Rocha, A Graves, J Morrow, J Janes, R Ruby, K Scoggin, A Johnson, K Orr, S Reed, G Hussey, L Goehring, BC Menarim and D Howe (2026) Investigation of the neuroinflammatory response in horses with selected neurologic diseases. CRWAD, January 17-20, Chicago, IL

B Shirah, I de Assis Rocha, H Gravatte, A Graves, J Morrow, H Kerber, SEI Bedoya, H El-Sheikh Ali, F Li, A Adams. R Ruby, J Janes. S Reed and DK Howe (2026) Assessment of the seroprevalence of Toxoplasma gondii in healthy and neurologic horses from diverse geographic locations. CRWAD, January 17-20, Chicago, IL

LG Eertink, JK Norris, S Soni, A Naveed, T Uprety, O Jacob, AJ Graves, JK Morrow, A Loynachan, SM Barnum, EN Adam, D Wang and F Li (2026) Genetic diversity of equine rotavirus A viruses collected within the United State of America between 2021 and 2025. CRWAD, January 17-20, Chicago, IL

LG Eertink, JK Norris, S Soni, A Naveed, T Uprety, O Jacob, AJ Graves, JK Morrow, SM Barnum, EN Adam. D Wang and F Li (2025) Genetic diversity of equine rotavirus A viruses collected within the United States of America between 2021 and 2025. Midwest Virology Symposium, September 26-28, Lexington, KY

S Reedy, B Sponseller, K Giri, Z Fang, S Soni, L Eertink, O Jacob, AJ Graves, JK Morrow, SM Barnum, Z Sheng, T Chambers, D Wang and F Li (2025) Investigation of 2024 equine influenza outbreaks in Kentucky. ASV, July 14-17, Montreal, Canada

F Li, Eertink, A Naveed, JK Norris, S Soni, T Uprety, O Jacob, AJ Graves, JK Morrow, SM Barnum, EN Adam and D Wang (2025) Genetic diversity of equine rotavirus A viruses collected within the United States of America between 2021 and 2024. ASV, July 14-17, Montreal, Canada

C Gamage, A Graves, J Morrow, G Li, CJ Thieulent, UBR Balasuriya and M Carossino (2025) Genomic characterization of equine rotavirus B circulating in central Kentucky. CRWAD, January 18-21, Chicago, IL

I de Assis Rocha, J Soto, A Graves, J Morrow, J James, R Ruby, K Scoggin, A Johnson, K Orr, S Reed, B Carvalho Menarim and D Howe (2025) Investigation of the cytokine profile of horses with neurologic diseases. ACVIM annual meeting, Louisville, KY

M Valdes Soto, J Morrow, A Graves and S DeNotta (2024) Clinical and diagnostic features of equine protozoal myeloencephalitis cases with Sarcocystis neurona rtPCR-positive cerebrospinal fluid. International Equine Infectious Disease Conference September 30-October 4, Deauville, France

A Graves, J Morrow and P Morresey (2024) Novel equine rotavirus B infection (2022-2023) International Equine Infectious Disease Conference September 30-October 4, Deauville, France

CK Enriquez, JK Morrow, AJ Graves and AL Johnson (2022) Evaluation of real time polymerase chain reaction (rtPCR) as a diagnostic tool for identification of Sarcocystis neurona in cerebrospinal fluid of horses with equine protozoal myeloencephalitis. EPM Havemeyer Workshop, October 18-21, Asheville, NC

SM Reed, AJ Graves and JK Morrow (2022) Usefulness of repeat testing by SAG 2/4/3 ELISA titer ratios of suspect EPM cases 2010-2021. EPM Havemeyer Workshop, October 18-21, Asheville, NC

S Reed, R Ruby, A Graves and J Morrow (2022) Comparison of the combined SAG 2,3,4 serum to CSF titer ratio with postmortem findings in horses in central Kentucky. EPM Havemeyer Workshop, October 18-21, Asheville, NC

K Orr, J Morrow, A Graves, S Reed and J Janes (2022) Confirmed or suspected concurrent equine protozoal myeloencephalitis and cervical vertebral malformation in horses with neurologic disease in central Kentucky. EPM Havemeyer Workshop, October 18-21, Asheville, NC

J Janes, R Ruby, J Morrow, A Graves and S Reed (2022) Horses with a postmortem diagnosis of EPM and SAG 2.3.4 serum titers less than or equal to 250. EPM Havemeyer Workshop, October 18-21, Asheville, NC

KM Delph, LA Beard, AC Trimble, ME Sutter, JF Timoney and JK Morrow (2018) Very high Streptococccus equi subspecies equi M protein titers (≥ 1:12, 800) with and without complications post-outbreak. ACVIM annual meeting, Seattle, WA

K JAMES, SM REED, JK MORROW AND N PUSTERLA (2017) ASSESSMENT OF THE DIAGNOSTIC VALUE OF NEUROLOGICAL SIGNS IN THE CLINICAL DIAGNOSIS OF EQUINE PROTOZOAL MYELOENCEPHALITIS. EPM WORKSHOP, OCTOBER 25-27, TAHOE CITY, CA

AJ Graves, SM Reed and JK Morrow (2017) Comparison of specific antibody index and Goldmann-Witmer coefficient (C-value) to evaluate intrathecal immunoglobulin G production in equine protozoal myeloencephalitis. EPM Workshop, October 25-27, Tahoe City, CA

SM Reed, R Candon, D-S Chan, JK Morrow, AJ Graves and H Anhold (2017) Evaluation of serum amyloid A as a biomarker for EPM diagnosis. October 25-27, Tahoe City, CA

S Schale, D Howe, M Yeargan, J Morrow, A Graves and AL Johnson (2017) Immunological investigation of protozoal co-infection in horses with equine protozoal myeloencephalitis in the eastern United States. EPM Workshop, October 25-27, Tahoe City, CA

R Lemcke, R Belgrave, J Morrow and N Pusterla (2017) Performance assessment of different diagnostic assays to identify EPM-affected horses in a clinical setting. EPM Workshop, October 25-27, Tahoe City, CA

AR Intan-Shameha, TJ Divers, JK Morrow, A Graves, E Olsen, AL Johnson and HO Mohammed (2107) Phosphorylated neurofilament H (pNF-H) as a potential diagnostic marker for neurological disorders in horses. EPM Workshop, October 25-27, Tahoe City, CA

AC Renier, JK Morrow, A Graves, CJ Finno, DK Howe, S Owens, E Tamez-Trevino, AE Packham, PA Conrad and N Pusterla (2012) Diagnosis of equine protozoal myeloencephalitis using indirect fluorescent antibody testing and enzyme-linked immunosorbent assay titer ratios for Sarcocystis neurona and Neospora hughesi. ACVIM annual meeting, New Orleans, LA

AL Johnson, JK Morrow and RW Sweeney (2012) Comparison of an IFAT and SAG ELISAs for antemortem diagnosis of EPM in naturally occurring cases. ACVIM annual meeting, New Orleans, LA

R Keene, J Tuttle, L Mittel, J Morrow and F Andrews (2012) Prevalence of serum neutralizing antibodies to equine rhinitis A and equine rhinitis B virus (ERV1 and ERV2) in select regions of the United States. ACVIM annual meeting, New Orleans, LA

SM Reed, DK Howe, MR Yeargan, JK Morrow, AJ Graves and WJA Saville (2010) New quantitative assays for the differential diagnosis of equine protozoal myeloencephalitis (EPM). ACVIM annual meeting, Anaheim, CA

H Aceto, B Dallap, K O'Shea, A Graves, J Morrow and S Rankin (2008) Validation of real-time PCR for targeted surveillance of Salmonella in equine colic patients. AAVLD annual meeting, Oct 24-29, Greensboro, NC

JK Morrow and SM Reed (2007) Prevalence of Sarcocystis neurona IgG in cerebrospinal fluid (CSF) submitted to Equine Biodiagnostics/IDEXX (EBI) from 2000-2005. ACVIM annual meeting, Seattle, WA

CM Brown, JK Morrow and CL Carleton (2006) Antibodies to Sarcocystis neurona are present in horses for many years following their removal from endemic areas. ACVIM annual meeting, Louisville, KY

JK Morrow, SM Reed and DE Granstrom (2006) Seroprevalence of Sarcocystis neurona IgG in United States submissions to Equine Biodiagnostics (EBI): a retrospective analysis of 2000-2005. ACVIM annual meeting, Louisville, KY

JF Timoney, A. Graves, S. Muthupalani and J Morrow (2004) Evaluation of SeM, Se75.3 and Se18.7 in ELISAs for serum antibody to Streptococcus equi. AAVLD annual meeting, October 21-28, Greensboro, NC

JS Hoane, JK Morrow and DK Howe (2004) Analysis of equine antibody isotype responses to Sarcocystis neurona surface antigens. Meeting of the AAVP, July 24-28, Philadelphia, PA

JS Hoane, JK Morrow, WS Saville and DK Howe (2004) Neospora hughesi seroprevalence in equids. Meeting of the AAVP, July 24-28, Philadelphia, PA

JS Hoane, M Yeargen, S Stamper, D Lindsay, B Saville, JK Morrow and DK Howe (2003) Modification of a recombinant antigen ELISA for detection of anti-Neospora hughesi antibodies in equine samples. Meeting of the American Association of Veterinary Parasitologists [AAVP], July 19-22, Denver, CO

S Witonsky, J Morrow, C Leger, J Dascanio, V Buechner-Maxwell, W Palmer, K Kline and A Cook (2002) Vaccination of horses with Sarcocystis neurona vaccine: analysis of specific IgG in serum and cerebrospinal fluid. Proceedings of the American College of Internal Medicine, p.29

MM Miller, CR Sweeney, GE Russell, RM Sheetz and JK Morrow (1998) Effect of iatrogenic blood-contaminated equine csf on Sarcocystis neurona western blot reactivity and csf indices. Proceedings of the American Association of Equine Practitioners 44:138-139